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Wasa,Masayuki

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个人简历


Ph.D., The Scripps Research Institute, 2013r
JSPS Postdoctoral Fellow, Harvard University, 2013-2015r
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SELECTED HONORS AND AWARDSr
2019 Sloan Research Fellowshipr
2018 National Institute of Health (NIGMS) Maximizing Investigators' Research Award for Early Stage Investigatorsr
Japan Society for the Promotion of Science Postdoctoral Fellowship for Research Abroad, (2013-2015), Harvard Universityr
Bristol-Myers Squibb Graduate Fellowship in Synthetic Organic Chemistry, (2009-2010), The Scripps Research Institute

研究领域


"""Our research program is centered on the development of polyfunctional Lewis pair catalysis for practical synthetic transformations with applications in drug discovery and development, and alternative energy. We will utilize these Lewis pair catalysts to enable reactions of inert substrates that cannot be activated efficiently by catalysts with a single activation center. Specifically, our initial efforts are focused on systematic identification of catalysts that will allow: a) transition metal-free asymmetric hydrogenation of various unsaturated substrates, b) reduction of CO2 to methanol, c) transition metal-catalyzed oxidative coupling of CO2 and olefins, and d) late-stage regioselective functionalization of C–H bonds in biopotent molecules."""

近期论文


Cao, M.; Yesilcimen, A.; Wasa, M. Enantioselective Conia-Ene-Type Cyclizations of Alkynyl Ketones through Cooperative Action of B(C6F5)3, N-Alkylamine and a Zn-Based Catalyst. J. Am. Chem. Soc. 2019, 140, 4199.r
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Shang, M.‡; Chan, J. Z.‡; Cao, M.; Chan, Y.; Wang, Q.; Cook, B.; Torker, S.; Wasa, M. C–H Functionalization of Amines via Alkene-Derived Nucleophiles through Cooperative Action of Chiral and Achiral Lewis Acid Catalysts: Applications in Enantioselective Synthesis. J. Am. Chem. Soc. 2018, 140, 10593.r
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Shang, M.; Cao, M.; Wang, Q.; Wasa, M. Enantioselective Direct Mannich-Type Reaction Catalyzed by Frustrated Lewis Acid/Brønsted Base Complexes. Angew. Chem., Int. Ed. 2017, 56, 13338. r
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Shang, M.; Wang, X.; Koo, S. M.; Youn, J.; Chan, J. Z.; Yao, W.; Hastings, B. T.; Wasa, M. Frustrated Lewis Acid/Brønsted Base Catalysts for Direct Enantioselective α-Amination of Carbonyl Compounds. J. Am. Chem. Soc.2017, 139, 95. r
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Chan, J. Z.; Yao, W.; Hastings, B. T.; Lok, C. K.; Wasa, M. Direct Mannich-Type Reactions Promoted by Frustrated Lewis Acid/Bronsted Base Catalysts. Angew. Chem., Int. Ed. 2016, 55, 13877.

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